Annals of internal medicine

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• Ann. Intern. Med. · Aug 2020

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  In high-risk patients with acute upper GI bleeding, urgent vs. early endoscopy did not differ for 30-day mortality.

  Lau JY, Yu Y, Tang RS, et al. Timing of endoscopy for acute upper gastrointestinal bleeding. N Engl J Med. 2020;382:1299-308. 32242355.

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• Ann. Intern. Med. · Aug 2020

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  In patients with ASCVD and elevated LDL-C with maximal statin therapy, inclisiran reduced LDL-C levels at 18 months.

  Ray KK, Wright RS, Kallend D, et al. Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol. N Engl J Med. 2020;382:1507-19. 32187462.

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• Ann. Intern. Med. · Aug 2020

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  Invasive therapy improved angina health status in patients with high-risk stable coronary disease and more frequent angina.

  Spertus JA, Jones PG, Maron DJ, et al. Health-status outcomes with invasive or conservative care in coronary disease. N Engl J Med. 2020;382:1408-19. 32227753.

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• Ann. Intern. Med. · Aug 2020

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  In patients with coronary disease and CKD, adding an invasive strategy to MT did not improve outcomes.

  Bangalore S, Maron DJ, O'Brien SM, et al. Management of coronary disease in patients with advanced kidney disease. N Engl J Med. 2020;382:1608-18. 32227756.

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• Ann. Intern. Med. · Aug 2020

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  In persistent sciatica and lumbar disk herniation, surgery vs. conservative care reduced leg pain at 6 mo.

  Bailey CS, Rasoulinejad P, Taylor D, et al. Surgery versus conservative care for persistent sciatica lasting 4 to 12 months. N Engl J Med. 2020;382:1093-102. 32187469.

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