Annals of internal medicine

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• Ann. Intern. Med. · Jan 2022

  Comment

  In uninfected household contacts of patients with COVID-19, REGEN-COV reduced symptomatic COVID-19 at 28 d.

  O'Brien MP, Forleo-Neto E, Musser BJ, et al. Subcutaneous REGEN-COV antibody combination to prevent Covid-19. N Engl J Med. 2021;385:1184-95. 34347950.

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• Ann. Intern. Med. · Jan 2022

  Comment

  In persons at intermediate risk for CVD, polypills reduce a composite of CV events at 5 y.

  Joseph P, Roshandel G, Gao P, et al. Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis. Lancet. 2021;398:1133-46. 34469765.

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• Ann. Intern. Med. · Jan 2022

  Comment

  In older patients at high risk for stroke, intensive AF screening with an implantable loop recorder did not reduce stroke.

  Svendsen JH, Diederichsen SZ, Højberg S, et al. Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial. Lancet. 2021;398:1507-16. 34469766.

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• Ann. Intern. Med. · Jan 2022

  Comment Letter

  Sodium-Glucose Cotransporter-2 Inhibitors Versus Glucagon-like Peptide-1 Receptor Agonists and the Risk for Cardiovascular Outcomes in Routine Care Patients With Diabetes Across Categories of Cardiovascular Disease.

  no abstract available

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• Ann. Intern. Med. · Jan 2022

  Editorial Comment

  Time for a Change: Optimizing Drug Data and Informed Choice in Pregnancy.

  no abstract available

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