Annals of internal medicine
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The strength and duration of immunity from infection with SARS-CoV-2 are important for public health planning and clinical practice. ⋯ Agency for Healthcare Research and Quality. (PROSPERO: CRD42020207098).
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Evidence about the association between types of oral anticoagulants and hazards of diabetes complications is limited in patients with atrial fibrillation (AF) and diabetes mellitus (DM). ⋯ Hualien Tzu Chi Hospital.
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Comment Randomized Controlled Trial
In inpatients with COVID-19 who need supplemental oxygen, lenzilumab increased ventilation-free survival.
Temesgen Z, Burger CD, Baker J, et al. Lenzilumab in hospitalised patients with COVID-19 pneumonia (LIVE-AIR): a phase 3, randomised, placebo-controlled trial. Lancet Respir Med. 2022;10:237-46. 34863332.
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Editorial Comment
The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia.
In their article, See and colleagues reported a study of thrombosis with thrombocytopenia syndrome (TTS), also known as vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare complication associated with receipt of the adenoviral-vectored COVID-19 vaccines ChAdOx1 nCoV-19 (Oxford/AstraZeneca) and Ad26. COV2. S (Janssen/Johnson & Johnson). The editorialists discuss the similarities of TTS with spontaneous heparin-induced thrombocytopenia.