Annals of surgery
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Biography Historical Article
Assessing the Magnitude of a Surgical Career Through His Trainees: The John L. Cameron Legacy Factor.
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Review Meta Analysis Comparative Study
Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials (PROSPERO 2015: CRD42015016882).
The aim was to investigate available evidence regarding effectiveness and safety of surgical versus conservative treatment of acute appendicitis. ⋯ Although antibiotics may prevent some patients from appendectomies, surgery represents the definitive, one-time only treatment with a well-known risk profile, whereas the long-term impact of antibiotic treatment on patient quality of life and health care costs is unknown. This systematic review and meta-analysis helps physicians and patients in choosing between treatment options depending on whether they are risk averse or risk takers.