Annals of surgery
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This study aimed to examine the expression profiles and prognostic value of multiple DDR proteins in resected PanNENs. ⋯ By analyzing large-scale tissue microarrays of PanNENs, we evaluated 12 DDR protein expression profiles. We developed a recurrence signature that can identify distinct subpopulations according to RFS, which may help refine individual follow-up.
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To assess the association between the timing of surgery relative to the development of Covid-19 and the risks of postoperative complications. ⋯ Major, elective surgery 0 to 4 weeks after SARS-CoV-2 infection is associated with an increased risk of postoperative complications. Surgery performed 4 to 8 weeks after SARS-CoV-2 infection is still associated with an increased risk of postoperative pneumonia, whereas surgery 8 weeks after Covid-19 diagnosis is not associated with increased complications.