Annals of surgery
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To determine the effect of elective abdominal surgery on the rate of human colon fractional protein synthesis in situ. ⋯ Elective abdominal surgery followed by an uncomplicated postoperative course is associated with a stimulation of colon protein synthesis and possibly also of protein degradation. The postoperative rate of colon protein synthesis is, compared with other tissues, among the highest measured thus far in humans.
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To demonstrate enhanced bone marrow monocytopoiesis in response to thermal injury and sepsis and to provide a mechanism for this observation. ⋯ The data validate the premise that enhanced monocytopoiesis in thermal injury and sepsis results from an imbalance in myelopoiesis that is driven by the increased expression of macrophage colony-stimulating factor receptor.
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To assess feasibility, risks, and patient outcomes in the treatment of colorectal metastases with two-stage hepatectomy. ⋯ Two-stage hepatectomy combined with chemotherapy may allow a long-term remission in selected patients with irresectable multiple metastases and increases the proportion of patients with resectable disease.
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To assess a technique for simultaneous recovery of the intestine, pancreas, and liver from the same donor. ⋯ It was possible using the described technique to retrieve intestine, pancreas, and liver allografts safely from the same donor and to transplant these organs to different recipients.