Annals of surgery
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The aim of our study was to conduct a systematic review and meta-analysis comparing the survival outcomes of IBD-associated and non-IBD-associated CRC. ⋯ IBD-CRC patients have a significant worse OS than patients with non-IBD CRC, which may be attributed to more aggressive histological characteristics and a lower rate of R0 resections at the primary tumor site. Optimized therapeutic standards and tailored follow-up strategies might improve the prognosis of IBD-CRC patients.
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Multicenter Study
Management of Pathogenic CDH1 Variant Carriers within the FREGAT Network: A multicentric Retrospective Study.
To describe the management of pathogenic CDH1 variant carriers (pCDH1vc) within the FREGAT (FRench Eso-GAsTric tumor) network. Primary objective focused on clinical outcomes and pathological findings, Secondary objective was to identify risk factor predicting postoperative morbidity (POM). ⋯ Among pCDH1vc, index cases carry a dismal prognosis. The risk of cancer among patients undergoing PTG remained high and unpredictable and has to be balanced with the morbidity and functional consequence of PTG.
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The objective of this study was to characterize the patterns of first recurrence after curative-intent resection for pancreatic adenocarcinoma (PDAC). ⋯ The pattern of recurrence in PDAC is predominantly DM rather than LR, and is consistent regardless of the use of NAC and margin involvement.
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Multicenter Study
Long-term Satisfaction with Roux-en-Y Gastric Bypass Surgery: Results from a Multicenter Prospective Cohort Study.
The aim of this study was to examine change in overall satisfaction with Roux-en-Y gastric bypass (RYGB) surgery over 3 to 7 years post-surgery and identify pre-surgery predictors and post-surgery factors associated with not being satisfied. ⋯ Level of satisfaction with RYGB surgery significantly decreased 3 to 7 years following surgery. Several pre- and post-surgery characteristics were associated with not being satisfied with surgery and provide potentially useful insight into individual patient experiences following RYGB. Knowledge of these characteristics may be useful in communication between surgeons and patients regarding post-surgical expectations and the impact of surgery on patients' lives.
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Ventral hernia repair (VHR) is one of the most commonly performed procedures in the United States, but studies assessing the long-term outcomes of VHR using biologic mesh are scarce. ⋯ Despite its use in complex AWR, ADM provides durable long-term outcomes with relatively low recurrence rates.