Annals of surgery
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Observational Study
Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis: A Prospective Observational Study.
To characterize endothelial function, inflammation, and immunosuppression in surgical patients with distinct clinical trajectories of AKI and to determine the impact of persistent kidney injury and renal non-recovery on clinical outcomes, resource utilization, and long-term disability and survival. ⋯ Among critically ill surgical sepsis patients, persistent AKI and the absence of renal recovery are associated with distinct early and sustained immunologic and endothelial biomarker signatures and decreased long-term physical function and survival.
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The aim of this study was to systematically review the available evidence about meditation's effects on surgeons. ⋯ More awareness and attention on this subject could improve surgeons' well-being as well as patients' outcomes.
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To compare the outcomes of livers donated after circulatory death (DCD) and undergoing either in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion (NMP) with livers undergoing static cold storage (SCS). ⋯ NRP and NMP were associated with better early liver function compared to SCS, whereas NRP was associated with superior preservation of the biliary system.
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We report a series of 355 consecutive patients treated over 9 years in a single institution with intended PDC. ⋯ PDC is feasible with low mortality and is associated with manageable complication rates. 5-year survival of patients undergoing PDC with MCR in multi-modality setting is approaching 25% depending on quantitative and clinical stage, sex and histological subtype and is better than PDC without- MCR.
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To evaluate pathological response to NAC in metastatic LNs, and assess its clinical prognostic significance in patients with EC. ⋯ Compared to PT response, pathological LN response better predicted long-term survival in EC patients who received NAC plus curative surgery.