Medical science monitor : international medical journal of experimental and clinical research
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The association of pain and socioeconomic status is widely reported, yet much less clearly understood. The aim of this study was to investigate the association of experimentally induced pain threshold and tolerance with socioeconomic status. ⋯ These results suggest a significant association between experimentally induced pain tolerance and tolerance interval with material status, suggesting that poor people indeed do hurt more.
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The complexity of multiple-item criteria in acute respiratory distress syndrome (ARDS) often causes inconvenience for physicians in the management of patients with severe acute pancreatitis (SAP). We evaluated whether serum SP-A levels in the presence of diffuse alveolar damage (DAD) can be qualitatively assessed for diagnosis of SAP-induced ARDS. ⋯ Serum SP-A levels may allow the detection of SAP-induced ARDS and may help to support the clinical diagnosis of ARDS. The optimal serum SP-A cut-off value to discriminate SAP-induced ARDS and other groups (SO group and non-ARDS group) is around 150 ug/ml.
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Leptin plays a critical role in neuronal development and also promotes structural and functional activities in the central nervous system. Recent studies have demonstrated that leptin could produce therapeutic effects for cognitive impairments of patients with Alzheimer's disease (AD). ⋯ Specifically, they are both characterized by cognitive impairment. In this regard, we hypothesized that leptin probably has a therapeutic benefit of alleviating symptoms of patients with POCD, and the leptin signaling pathway may be involved in the pathogenesis of POCD.
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The neural underpinnings of auditory information processing have often been investigated using the odd-ball paradigm, in which infrequent sounds (deviants) are presented within a regular train of frequent stimuli (standards). Traditionally, this paradigm has been applied using either high temporal resolution (EEG) or high spatial resolution (fMRI, PET). However, used separately, these techniques cannot provide information on both the location and time course of particular neural processes. The goal of this study was to investigate the neural correlates of auditory processes with a fine spatio-temporal resolution. A simultaneous auditory evoked potentials (AEP) and functional magnetic resonance imaging (fMRI) technique (AEP-fMRI), together with an odd-ball paradigm, were used. ⋯ The present study showed that neural processes evoked by standard stimuli occur predominantly in subcortical and cortical structures of the auditory pathway. Deviants activate areas non-specific for auditory information processing.
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Minimally invasive surgery (MIS) of anterior ring fracture combined with pubic symphysis separation.
The aim of this study was to evaluate the reliability of open reduction and minimally invasive plate osteosynthesis (MIPO) for anterior ring fracture combined with pubic symphysis separation and to explore the operative techniques and therapeutic efficacy. ⋯ The MIS or MIPPO for anterior ring fracture combined with pubic symphysis separation has the advantages of short operation time and less blood loss. This clinical operation is safe and feasible, with therapeutic efficacy.