Journal of evaluation in clinical practice
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The clinical data management within biomedical research has gained importance over the last decade producing an increasing need of a web-based software application providing electronic data capture and clinical data management functionalities to ensure high quality data. We chose REDCap system over OpenClinica (free-distribution) to implement the electronic case report form (eCRF) at our HIV Unit. We then evaluated eCRF usability and stakeholder satisfaction in an upcoming Phase 4 clinical trial. ⋯ When adopting a new system, measuring user's perceived usability and satisfaction in a quantitative manner and with validated measures may be useful to identify users' uncovered needs and to improve future interaction user-system that will positively affect the quality of data managed in clinical research.
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Antibiotic prescription, its nature and its duration are a very common decision-making situation in primary care practice. Clinical practice guidelines (CPGs) are regularly emitted by various organisations on this topic. ⋯ There is a lack of quality in the development process of the current French guidelines in primary care infectiology. This process should be reconsidered, with higher insistence as to its quality.
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This study aimed to adapt the 6-Item Self-Efficacy Scale for Chronic Disease Management (SEMDC-6S) to women with endometriosis in the Turkish population and to evaluate its validity and reliability. ⋯ The Turkish version of the SEMDC-6S is a valid and reliable tool for assessing the self-efficacy of women with endometriosis.
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3D Magnetic Resonance Imaging (3D-MRI) analysis of brain tumours is an important tool for gathering information needed for diagnosis and disease therapy planning. However, during the brain tumor segmentation process existing techniques have segmentation error while identifying tumor location and extended tumor regions due to improper extraction of initial contour points and overlapping tissue intensity distributions. ⋯ The results obtained for the BraTS2020 and Brain Tumor Detection 2020 data sets showed that the proposed model outperforms existing techniques with excellent precision of 97%, 97.5%, recall of 99%, 97.8%, and accuracy of 95.7%, 98.4%, respectively.
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NICE guidelines recommend offering computerised Cognitive Behavioural Therapy (cCBT) to young people with mild mental health issues to ensure early treatment access and reduce service demand. Emerging evidence suggests cCBT reduces symptoms, but further evaluation is needed. SilverCloud is a recommended digital CBT programme. ⋯ This evaluation suggests tentative pessimism regarding SilverCloud's benefits. However, due to significant challenges and limitations, further analysis is recommended. Recommendations were given for local services.