Journal of evaluation in clinical practice
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Comment Letter
Unwarranted variation from a health economics perspective.
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To establish an enhanced Youden's index with net benefit, as a scientific method for optimal-threshold determination in shared decision making. ⋯ The enhanced Youden's index can establish the optimal-thresholds from the perspective of maximization of patients' net benefit and provide a quantifiable method for shared decision making.
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Every individual experiences good luck and bad luck. Three features characterize medical events associated with good luck or bad luck: There is no control over the event, the event occurs through chance or accident, and the event is of significant interest. These characteristics can be used to develop a working definition of medical luck. ⋯ A total valence of zero before or after intervention does not, however, imply absent medical luck but simply a combination of medical good luck and medical bad luck because significance interest in the event persists. Therefore, there is no medical luck simpliciter, only medical good luck and medical bad luck. Medical events are especially helpful to understanding good luck and bad luck, because they are non-fictional, often generate significant interest, and are modifiable.