International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
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Int. J. Infect. Dis. · Mar 2009
Acute kidney injury in patients with sepsis: a contemporary analysis.
To analyze the clinical characteristics of septic acute kidney injury (AKI) according to the Acute Kidney Injury Network (AKIN) classification, and to evaluate the capacity of this system in predicting in-hospital mortality of septic patients. ⋯ AKIN criteria are a useful tool to characterize and stratify septic patients according to the risk of death.
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Echinococcosis in humans occurs as a result of infection by the larval stages of taeniid cestodes of the genus Echinococcus. In this review we discuss aspects of the biology, life cycle, etiology, distribution, and transmission of the Echinococcus organisms, and the epidemiology, clinical features, treatment, and effect of improved diagnosis of the diseases they cause. New sensitive and specific diagnostic methods and effective therapeutic approaches against echinococcosis have been developed in the last 10 years. Despite some progress in the control of echinococcosis, this zoonosis continues to be a major public health problem in several countries, and in several others it constitutes an emerging and re-emerging disease.
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Int. J. Infect. Dis. · Mar 2009
Infections in a surgical intensive care unit of a university hospital in Greece.
We aimed to evaluate the clinical and microbiological characteristics of the patients who developed an infection in our surgical intensive care unit (SICU). ⋯ Infections are an important problem in SICUs due to high incidence, multi-drug resistance, complications, and mortality rate. In our study, APACHE II score on admission, peritonitis, acute pancreatitis, previous aminoglycoside use, and mechanical ventilation were identified as risk factors for infection development, whereas age, APACHE II score on admission, SOFA score at the onset of infection, and VAP were associated with mortality.
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Int. J. Infect. Dis. · Jan 2009
The economic impact of aspergillosis: analysis of hospital expenditures across patient subgroups.
To measure the impact of invasive aspergillosis infection on US hospital costs and financial performance across different patient populations. ⋯ Aspergillosis affects a wide range of patient groups and has a negative economic impact across many DRGs. Improved prevention, diagnosis, and patient management strategies can help mitigate these effects on hospital financial performance.
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To investigate the incidence, risk factors, causative fungi, and outcomes of fungemia in adult, non-HIV-infected patients. ⋯ Candidemia, especially that caused by non-albicans Candida, was an important nosocomial infection in this tertiary care hospital in Northeast Thailand. The mortality rate was high, particularly in patients who were critically ill. Rapid diagnosis and early treatment are therefore important challenges for improving clinical outcomes.