The journal of obstetrics and gynaecology research
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J. Obstet. Gynaecol. Res. · Aug 2016
Case ReportsFirst report of icatibant treatment in a pregnant patient with hereditary angioedema.
Hereditary angioedema resulting from C1-inhibitor deficiency (C1-INH-HAE) is a rare, autosomal dominant disorder, characterized by recurrent attacks of edema formation. The management of pregnant patients with C1-INH-HAE is often a challenge for the physician. There is limited experience with novel therapies. ⋯ No side effects were detected with either treatment. No reports have been published to date on multiple dosing with icatibant during the first trimester of pregnancy. This therapy proved effective and free of maternal or fetal adverse effects.
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J. Obstet. Gynaecol. Res. · Aug 2016
Iatrogenic parasitic leiomyoma and leiomyomatosis peritonealis disseminata following uterine morcellation.
To assess the impact of morcellation on the spread of uterine leiomyoma. ⋯ Laparoscopic hysterectomy with tumor morcellation may increase the chance of tumor implantation and dissemination. Both clinicians and pathologists should be alert to this rare complication.
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J. Obstet. Gynaecol. Res. · Jul 2016
Multicenter StudySeatbelt use and seat preference among pregnant women in Sapporo, Japan, in 2013.
This study was performed to determine the rate of pregnant occupants in motor vehicle accidents (MVA) and the frequency of seatbelt use in pregnancy in Japan. ⋯ The careful attitude of pregnant women toward driving safety may be associated with reduced risk of MVA in pregnancy. There is a need for an intensified campaign to promote seatbelt use among pregnant women.
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J. Obstet. Gynaecol. Res. · Jul 2016
Pre-delivery fibrinogen predicts adverse maternal or neonatal outcomes in patients with placental abruption.
Placental abruption is a severe obstetric complication of pregnancy that can cause disseminated intravascular coagulation and progress to massive post-partum hemorrhage. Coagulation disorder due to extreme consumption of fibrinogen is considered the main pathogenesis of disseminated intravascular coagulation in patients with placental abruption. The present study sought to determine if the pre-delivery fibrinogen level could predict adverse maternal or neonatal outcomes in patients with placental abruption. ⋯ Pre-delivery fibrinogen can predict adverse maternal as well as neonatal outcomes with placental abruption. © 2016 Japan Society of Obstetrics and Gynecology.
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To characterize the most common causes and risk factors of maternal mortality in the USA and observe trends over the past 9 years. ⋯ Maternal mortality remains a rare event. Although sepsis was the overall predominant cause of mortality during the study period, frequency declined over time and it was surpassed by hemorrhage and hypertensive disorders as the leading causes of maternal mortality.