Respirology : official journal of the Asian Pacific Society of Respirology
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Analysis of exhaled breath condensate (EBC) pH is a non-invasive method to study airway inflammation. Low pH is correlated with inflammatory diseases like asthma and COPD. The aim of this study was to assess the influence of measurement temperature on pH values of EBC. ⋯ Our data indicate a considerable influence of temperature on pH values in EBC. Thus the temperature at which pH measurements in EBC studies are performed should be declared.
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Continuous monitoring of PaO(2) in seriously ill patients is an important aspect of clinical management, especially for patients with acute lung injury (ALI) or acute respiratory distress syndrome. We have developed a fibreoptic sensor to detect PaO(2)in vivo based on fluorescence quenching technology. In this study we evaluated the sensitivity of this sensor in monitoring PaO(2) in a rabbit model with ALI. ⋯ The oxygen sensor showed high accuracy and stability for continuous monitoring of PaO(2) in normal animals, in animals with ALI and in animals with electrolyte disturbance, suggesting that it may be clinically useful in the continuous measurement of oxygen partial pressure.