Respirology : official journal of the Asian Pacific Society of Respirology
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Weaning from invasive mechanical ventilation (IMV) in specialized weaning units has been demonstrated to be safe and cost-effective. Success rates and outcomes vary widely, probably relating to patient factors and unit expertise. ⋯ High rates of weaning success with infrequent complications and low mortality were achieved in this specialized non-intensive care unit-based weaning unit. The VWU may provide a useful template for the development of similar units elsewhere.
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Respiratory inductive plethysmography is a non-invasive technique for measuring respiratory function. However, there are challenges associated with using linear methods for calibration of respiratory inductive plethysmography. In this study, we developed two nonlinear models, artificial neural network and adaptive neuro-fuzzy inference system, to estimate respiratory volume based on thoracoabdominal movements, and compared these models with routine linear approaches, including qualitative diagnostic calibration and multiple linear regression. ⋯ These results indicate that the nonlinear methods can be adapted to closely simulate variable conditions and used to study the patterns of volume changes during normal and asynchronous breathing.
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Meta Analysis
Obstructive sleep apnoea and the risk of type 2 diabetes: a meta-analysis of prospective cohort studies.
There has been increasing recognition that obstructive sleep apnoea (OSA) is associated with incident type 2 diabetes. The aim of this study was to assess the association between the severity of OSA and the risk of type 2 diabetes by performing a meta-analysis of all available prospective cohort studies. ⋯ This meta-analysis indicates that moderate-severe OSA is associated with an increased risk of type 2 diabetes, and this appears to be an independent risk factor for the development of diabetes.
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Identifying citation classics in the field is one of the key methodologies used to conduct a systematic evaluation of research performance. The objective of this study was to determine the most frequently cited articles published in journals that are placed under the 'respiratory system' subject category (Institute for Scientific Information (ISI) Journal Citation Reports) and to compare them with the most frequently cited respiratory-related articles published in any journal, regardless of subject category. The authors utilized the ISI Journal Citation Reports: Science Edition 2010 database in April 2012 to determine the most frequently cited articles by respiratory system subject category and by respiratory-related keywords. ⋯ The median numbers of citations for the top 50 cited articles stratified by respiratory system subject category and respiratory-related keywords were 841.5 and 2701, respectively. Half of the top 50 cited articles identified by respiratory-related keywords were published in general medical or basic science journals, whereas only three out of these were published in journals under the respiratory system subject category in ISI Journal Citation Reports. In summary, respiratory-related articles published in general medical or science journals attracted more citations than those published in the specific respiratory journals.
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Lung transplantation has become an accepted therapeutic procedure for the treatment of end-stage pulmonary parenchymal and vascular disease. Despite improved survival rates over the decades, lung transplant recipients have lower survival rates than other solid organ transplant recipients. ⋯ The epidemiology, diagnosis, prophylaxis, treatment and outcomes for the different microbial pathogens will be reviewed. The effects of infection on lung transplant rejection will also be discussed.