Archives of disease in childhood
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Observational Study
Cardiopulmonary exercise testing in children with cystic fibrosis: one centre's experience.
While exercise testing is increasingly used as a prognostic indicator in cystic fibrosis (CF), it is reported to be underused in UK CF centres, particularly in children. Here, we evaluated the cardiopulmonary exercise testing (CPET) results in children and young people with CF at CF annual review and its possible clinical value. ⋯ CPET is feasible with 95% of children and young people achieving technically satisfactory assessments starting from age 7. In this group with relatively mild CF, mean Vo2peak was normal with no significant correlation between Vo2peak and FEV1 or BMI, as markers of disease severity. The majority demonstrated a normal Vo2peak. However, 71% showed a downward trend on repeat testing 12-18 months later.
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Randomized Controlled Trial Multicenter Study
Randomised controlled trial and economic evaluation of the 'Families for Health' programme to reduce obesity in children.
Evaluating effectiveness and cost-effectiveness of 'Families for Health V2' (FFH) compared with usual care (UC). ⋯ FFH was neither effective nor cost-effective for the management of obesity compared with UC.
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Randomized Controlled Trial
Randomised crossover trial of rate feedback and force during chest compressions for paediatric cardiopulmonary resuscitation.
To determine the effect of visual feedback on rate of chest compressions, secondarily relating the forces used. ⋯ While visual feedback restricted excessive compression rates to within the prescribed range, applied force remained widely variable. The forces required may differ with growth, but such variation treating one manikin is alarming. Feedback technologies additionally measuring force (effort) could help to standardise and define effective treatments throughout childhood.
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To analyse the outpatient management of selected febrile infants younger than 90 days without systematic lumbar puncture and antibiotics. ⋯ Outpatient management without antibiotics and systematic lumbar puncture is appropriate for selected febrile infants younger than 3 months of age with close follow-up.