Health technology assessment : HTA
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Health Technol Assess · Oct 2020
Randomized Controlled Trial Multicenter StudyAnnual mammographic screening to reduce breast cancer mortality in women from age 40 years: long-term follow-up of the UK Age RCT.
There remains disagreement on the long-term effect of mammographic screening in women aged 40-49 years. ⋯ There is a need for research on the effects of modern mammographic protocols and additional imaging in this age group.
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Health Technol Assess · Oct 2020
Randomized Controlled Trial Multicenter Study Clinical TrialStratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT.
Sciatica has a substantial impact on patients and society. Current care is 'stepped', comprising an initial period of simple measures of advice and analgesia, for most patients, commonly followed by physiotherapy, and then by more intensive interventions if symptoms fail to resolve. No study has yet tested a model of stratified care in which patients are subgrouped and matched to different care pathways based on their prognosis and clinical characteristics. ⋯ Other approaches to stratified care may provide superior outcomes for sciatica.
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Health Technol Assess · Oct 2020
Randomized Controlled Trial Multicenter StudySurgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT.
Scaphoid fractures account for 90% of carpal fractures and occur predominantly in young men. Immediate surgical fixation of this fracture has increased. ⋯ Adult patients with an undisplaced or minimally displaced scaphoid waist fracture should have cast immobilisation and suspected non-unions immediately confirmed and urgently fixed. Patients should be followed up at 5 years to investigate the effect of partial union, degenerative arthritis, malunion and screw problems on their quality of life.
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Health Technol Assess · Sep 2020
Interventions for adults with a history of complex traumatic events: the INCiTE mixed-methods systematic review.
People with a history of complex traumatic events typically experience trauma and stressor disorders and additional mental comorbidities. It is not known if existing evidence-based treatments are effective and acceptable for this group of people. ⋯ This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 43. See the NIHR Journals Library website for further project information.
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Health Technol Assess · Sep 2020
Clinical TrialOccupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study.
Hip and knee replacements are regularly carried out for patients who work. There is little evidence about these patients' needs and the factors influencing their return to work. There is a paucity of guidance to help patients return to work after surgery and a need for structured occupational advice to enable them to return to work safely and effectively. ⋯ This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 45. See the NIHR Journals Library website for further project information.