Journal of laparoendoscopic & advanced surgical techniques. Part A
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J Laparoendosc Adv Surg Tech A · Feb 2008
Randomized Controlled Trial Comparative StudyDoes preoperative hydration affect postoperative nausea and vomiting? A randomized, controlled trial.
It has been suggested that relative hypovolemia due to overnight fasting may result in postoperative nausea and vomiting (PONV). The aim of this study was to investigate the effect of preoperative and intraoperative hydration (the necessary amount of fluid preoperatively to cover the fluid deficit) on PONV. ⋯ PONV was reduced when the fluid deficit was replaced preoperatively.
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J Laparoendosc Adv Surg Tech A · Dec 2007
Randomized Controlled Trial Comparative StudyComparison of the effectiveness of metoclopramide, ondansetron, and granisetron on the prevention of nausea and vomiting after laparoscopic cholecystectomy.
A relatively high incidence of postoperative nausea and vomiting (PONV) occurs in patients undergoing a laparoscopic cholecystectomy. Prophylaxis of PONV is usually achieved with a single-dose antiemetic drug administered during the surgical procedure. The aim of the current study was to compare the antiemetic activity of different 5-hydroxytryptamine-3 receptor antagonists with that of metoclopramide. ⋯ Granisetron, when given prophylactically, resulted in a significantly lower incidence of PONV than metoclopramide and ondansetron, whereas metoclopramide was ineffective. Garnisetron may be an effective treatment in the proflaxy of PONV.
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J Laparoendosc Adv Surg Tech A · Aug 2005
Randomized Controlled Trial Comparative StudyAnalgesic efficacy of caudal block versus diclofenac suppository and local anesthetic infiltration following pediatric laparoscopy.
To compare the analgesic efficacy of caudal block with diclofenac suppository and local anesthetic infiltration in children undergoing laparoscopy. ⋯ We find the analgesic efficacy of diclofenac suppository combined with local anesthetic infiltration at port sites comparable to caudal block. Given the necessarily invasive nature of caudal block, we suggest the combined use of diclofenac suppository with local anesthetic infiltration at port sites as a useful and more economical alternative for analgesia following pediatric laparoscopy.
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J Laparoendosc Adv Surg Tech A · Apr 2005
Randomized Controlled Trial Comparative Study Clinical TrialThe effect of low-flow sevoflurane and desflurane on pulmonary mechanics during laparoscopic surgery.
This study was designed to investigate the effects of inhaled anesthetic agents on respiratory mechanics with low flow anesthesia in laparoscopic abdominal surgery. Two inhaled anesthetics, desflurane and sevoflurane, have a lower solubility in blood and tissues than all previous volatile anesthetics, and have become the preferred volatile anesthetics for routine surgical procedures. ⋯ We concluded that respiratory mechanics were affected by desflurane with low flow anesthesia in patients undergoing laparoscopic abdominal surgery. No significant influence on respiratory mechanics was seen with sevoflurane anesthesia.
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J Laparoendosc Adv Surg Tech A · Feb 2005
Randomized Controlled Trial Clinical TrialHeated and humidified insufflation during laparoscopic gastric bypass surgery: effect on temperature, postoperative pain, and recovery outcomes.
Controversy exists regarding the efficacy of heated and humidified intraperitoneal gases in maintaining core body temperature. We performed a sham-controlled study to test the hypothesis that active warming and humidification of the insufflation gas reduces intraoperative heat loss and improves recovery outcomes. ⋯ The Insuflow device modestly reduced shivering and heat loss, as well as the need for opioid analgesics in the early postoperative period. However, it failed to improve laparoscopic visualization due to fogging, and provided improvement in the quality of recovery only on postoperative day 2.