British journal of anaesthesia
-
We describe the successful use of methadone in the restoration of sedation and provision of analgesia in two morphine-tolerant, paediatric patients who had suffered significant thermal injuries and were undergoing mechanical ventilation. Both patients had exhibited escalating requirements for sedative drugs while undergoing ventilation yet remained inadequately sedated. ⋯ Hyperalgesia and morphine tolerance appear to be associated; it is proposed that methadone acts primarily, under these circumstances, by re-establishing the analgesic state. Such use of methadone in the morphine-tolerant patient also afforded a concomitant sedative-sparing effect.
-
We have measured the performance of 10 trainee anaesthetists during a single simulated anaesthetic during which there was a complex critical incident. Errors in the recording on the anaesthetic charts of the "patient's" oxygen saturation, heart rate, systolic and diastolic arterial pressures and end-tidal carbon dioxide concentrations were used as a measure of mental workload and hence performance. The critical incident was designed to be stressful and contained, in sequence, episodes of hypotension, arrhythmia and bronchospasm. ⋯ There was no evidence of a tendency to consistently underestimate the magnitude of abnormal values. This method is appropriate for assessing the performance of groups of anaesthetists during simulated critical incidents. It also raises questions on the accuracy of anaesthetic record charts when recording critical incidents.