British journal of anaesthesia
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Estimation of changes in cardiac output from the arterial blood pressure waveform in the upper limb.
We have developed a new pulse contour cardiac output (PulseCO) algorithm based on frequency analysis studies of the arterial system. PulseCO was compared with thermodilution cardiac output (TDCO) in 10 patients undergoing cardiac surgery. Results from one patient were unsuitable for analysis. ⋯ Least squares regression gave y = 0.71 x (r2 = 0.70) and the limits of agreement were from -21% to +25%. After phenylephrine had been given to five patients, PulseCO showed an increase in systemic vascular resistance consistent with the known pharmacological actions of the drug. The PulseCO algorithm was incorporated into a computer program that acquires arterial pressure data from an analogue-to-digital converter and displays beat-to-beat trend values.