British journal of anaesthesia
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Randomized Controlled Trial
The effect of ephedrine on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium.
We compared the effect of pre-treatment with ephedrine 75, 100, 150 microg kg(-1) and saline on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium. ⋯ Ephedrine either 75 or 100 microg kg(-1) given before rapid tracheal intubation using propofol and rocuronium bromide improves the intubation conditions. It is not effective in preventing the hypotension which follows ensuing induction of anaesthesia.
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Randomized Controlled Trial Comparative Study
Comparison of desflurane with sevoflurane for the incidence of oculocardiac reflex in children undergoing strabismus surgery.
The oculocardiac reflex (OCR) is frequently observed during strabismus surgery. This study was designed to evaluate and compare the effect of sevoflurane and desflurane on the incidence of OCR. ⋯ Both agents can be used safely during strabismus surgery in paediatric patients.
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Randomized Controlled Trial
Comparison of intubating laryngeal mask airway and Bullard laryngoscope for oro-tracheal intubation in adult patients with simulated limitation of cervical movements.
Intubation of a patient with limited cervical spine movement or in whom movement of the cervical spine is not desirable is always a challenge even to the most experienced anaesthesiologist. The intubating laryngeal mask airway (ILMA) and the Bullard laryngoscope (BL) are two instruments recommended for endotracheal intubation of such patients. We compared their utility and safety in patients with simulated cervical spine immobility using manual inline stabilization (MILS). ⋯ Both the BL and the ILMA are useful equipment in intubating patients with limitation of cervical movements. Although not statistically significant, the BL may provide a higher success rate of intubation when compared with the ILMA.
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The delay between changes in end-expired sevoflurane concentrations and bispectral index (BIS) may be characterized by a 'rate constant' (ke0). A smaller ke0 reflects a longer delay. Values for ke0 vary substantially among studies. The question arises how ke0 depends on experimental conditions, including ventilation and apparatus. ⋯ Published ke0s (0.22-0.53 min(-1)), including our own for sevoflurane-depressed spontaneous ventilation (0.48 min(-1)), are in the ranges dictated by investigation-specific conditions.