British journal of anaesthesia
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Comment Letter Comparative Study
Oral clonidine vs midazolam in the prevention of sevoflurane-induced agitation in children.
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Editorial Retracted Publication
The balanced concept of fluid resuscitation.
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Randomized Controlled Trial Comparative Study
Faster wash-out and recovery for desflurane vs sevoflurane in morbidly obese patients when no premedication is used.
The aim of this study was to compare desflurane vs sevoflurane kinetics and dynamics in morbidly obese patients and their recovery profile when no premedication had been used. ⋯ Desflurane provides faster wash-in and wash-out than sevoflurane in morbidly obese patients, and recovery is much faster after desflurane administration when no premedication has been used.
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Multicenter Study Comparative Study
Regional anaesthesia for carotid endarterectomy: an audit over 10 years.
The aim of this retrospective study was to compare the failure rates and the frequency of anaesthesia-related complications of two different methods of regional anaesthesia used for carotid endarterectomy--cervical epidural (CE) anaesthesia and cervical plexus block (CPB). ⋯ Both methods of regional anaesthesia are acceptable for carotid artery surgery. CPB is associated with a significantly lower frequency of anaesthesia-related complications and should therefore be considered the anaesthetic of choice. CE anaesthesia should not be performed except in extenuating circumstances such as variant anatomy or the requirement for more extensive surgery.
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Randomized Controlled Trial
Effects of propofol and desflurane anaesthesia on the alveolar inflammatory response to one-lung ventilation.
One-lung ventilation (OLV) induces a pro-inflammatory response including cytokine release and leucocyte recruitment in the ventilated lung. Whether volatile or i.v. anaesthetics differentially modulate the alveolar inflammatory response to OLV is unclear. ⋯ These data indicate that pro-inflammatory reactions during OLV were influenced by the type of general anaesthesia. Different patterns of alveolar cytokines may be a result of increased granulocyte recruitment during propofol anaesthesia.