British journal of anaesthesia
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Randomized Controlled Trial Observational Study
Intraoperative hypotension and delirium after on-pump cardiac surgery†.
Delirium is a common complication after cardiac surgery and may be as a result of inadequate cerebral perfusion. We studied delirium after cardiac surgery in relation to intraoperative hypotension (IOH). ⋯ Independent of the applied definition, IOH was not associated with the occurrence of delirium after cardiac surgery.
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Randomized Controlled Trial Multicenter Study
Effects of supplemental oxygen and dexamethasone on surgical site infection: a factorial randomised trial.
Tissue oxygenation is a strong predictor of surgical site infection. Improving tissue oxygenation should thus reduce wound infection risk. Supplemental inspired oxygen can improve tissue oxygenation, but whether it reduces infection risk remains controversial. Low-dose dexamethasone is often given to reduce the risk of postoperative nausea and vomiting, but steroid-induced immunosuppression can increase infection risk. We therefore tested the hypotheses that supplemental perioperative oxygen reduces infection risk and that dexamethasone increases it. ⋯ ClinicalTrials.gov number: NCT00273377.