British journal of anaesthesia
-
Observational Study
Predictive performance of eleven pharmacokinetic models for propofol infusion in children for long-duration anaesthesia.
Predictive performance of eleven published propofol pharmacokinetic models was evaluated for long-duration propofol infusion in children. ⋯ The Short model performed well during continuous infusion up to 545 min. This model might be preferable for target-controlled infusion for long-duration anaesthesia in children.
-
Perioperative aspiration leads to significant morbidity and mortality. Point-of-care gastric ultrasound is an emerging tool to assess gastric content at the bedside. ⋯ This retrospective cohort study suggests that a small proportion of elective surgical patients may present with a full stomach despite the recommended duration of fasting. Further research is needed to establish the clinical implications of these findings in the elective setting. At present, the clinical role of gastric ultrasound continues to be for the evaluation of gastric contents to guide management when the risk of aspiration is uncertain or unknown.