British journal of anaesthesia
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Randomized Controlled Trial Multicenter Study Comparative Study
Individualised or liberal red blood cell transfusion after cardiac surgery: a randomised controlled trial.
Current practice guidelines for red blood cell (RBC) transfusion in ICUs are based on haemoglobin threshold, without consideration of oxygen delivery or consumption. We aimed to evaluate an individual physiological threshold-guided by central venous oxygen saturation ScvO2. ⋯ NCT02963883.
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Comparative Study Observational Study
Determining optimal positive end-expiratory pressure and tidal volume in children by intratidal compliance: a prospective observational study.
Limited data exist regarding optimal intraoperative ventilation strategies for the paediatric population. This study aimed to determine the optimal combination of PEEP and tidal volume (VT) based on intratidal compliance profiles in healthy young children undergoing general anaesthesia. ⋯ NCT04633720.
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Randomized Controlled Trial Comparative Study
Efficacy of high-flow nasal oxygenation compared with tracheal intubation for oxygenation during laryngeal microsurgery: a randomised non-inferiority study.
Oxygenation via a high-flow nasal cannula (HFNC) can be an alternative to tracheal intubation during short apnoeic procedures. This randomised, non-inferiority study assessed the efficacy of HFNC compared with tracheal intubation in laryngeal microsurgery. ⋯ NCT03629353.