British journal of anaesthesia
-
Whether long-term opioid use is an independent risk factor for cancer progression remains unclear. Therefore, we conducted a propensity score-matched population-based cohort study to compare cancer incidence between patients with chronic pain with and without opioid use. ⋯ There was an association between long-term opioid use and development of cancer in patients with chronic pain, which should be confirmed in future studies.
-
Enhanced recovery programmes reduce hospitalisation and medical complications across procedures, but unfortunately there have well-documented difficulties in implementation. Some recovery programmes include many components that hinder widespread implementation. The delivery of Drinking, Eating, and Mobilising (DrEaMing) bundle, with its focus on drinking, eating, and mobilising, may serve as a simple combined process, outcome measure, or both, thereby facilitating further progress in monitoring, auditing, implementation, and improvement of enhanced recovery programmes.
-
Review Meta Analysis
Liberal or restrictive antimicrobial prophylaxis for surgical site infection: systematic review and meta-analysis of randomised trials.
Antimicrobial prophylaxis is widely used to prevent surgical site infection. Amid growing concern about antimicrobial resistance, we determined the effectiveness of antimicrobial prophylaxis. ⋯ A systematic review and meta-analysis of randomised trials revealed that more liberal antimicrobial prophylaxis is associated with a small reduction in the risk of surgical site infection, although antimicrobial harms are poorly reported. Further evidence about the risks of antimicrobial prophylaxis to inform current widespread use is urgently needed.
-
There is no consensus about the type of instrument with which to assess postoperative recovery or the time points when assessments are most appropriate. It is also unclear whether instruments measure the four dimensions of postoperative recovery, that is physical, psychological, social, and habitual recovery. This scoping review had three objectives: (1) to identify and describe instruments used in clinical trials to assess postoperative recovery; (2) to determine how, when, and the number of times postoperative recovery was measured; and (3) to explore whether the four dimensions of postoperative recovery are represented in the identified instruments. ⋯ Assessing recovery is important to evaluate and improve perioperative care. We emphasise the importance of choosing the right instrument for the concept studied and, if postoperative recovery is of interest, of assessing more than once. Ideally, instruments should include all four dimensions to cover the whole recovery process.