British journal of anaesthesia
The most recent articles from:
Br J Anaesth
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Review Meta Analysis
Effects of dexmedetomidine on perioperative stress, inflammation, and immune function: systematic review and meta-analysis.
Dexmedetomidine reduces perioperative stress and inflammation, while supporting surgical patients’ immune function.
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Review Meta Analysis
Perioperative adverse events attributed to α2-adrenoceptor agonists in patients not at risk of cardiovascular events: systematic review and meta-analysis.
Several systematic reviews have reported the benefits of perioperative α2-adrenoceptor agonist use for various conditions, but safety evidence is poorly documented. ⋯ CRD42017071583.
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Evidence-based international expert consensus regarding anaesthetic practice in hip/knee arthroplasty surgery is needed for improved healthcare outcomes. ⋯ neuraxial anaesthesia is recommended for hip arthroplasty given associated outcome benefits; evidence level: moderate-low, strong recommendation. Based on current evidence, the consensus group recommends neuraxial over general anaesthesia for hip/knee arthroplasty.