British journal of anaesthesia
The most recent articles from:
Br J Anaesth
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Letter Meta Analysis
Presenting symptoms of COVID-19 in children: a meta-analysis of published studies.
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Postoperative neurocognitive disorders may arise in part from adverse effects of general anaesthetics on the CNS, especially in older patients or individuals otherwise vulnerable to neurotoxicity because of systemic disease or the presence of pre-existing neuropathology. Previous studies have documented cytokine and injury biomarker responses to surgical procedures that included general anaesthesia, but it is not clear to what degree anaesthetics contribute to these responses. ⋯ NCT02275026.