British journal of anaesthesia
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Multicenter Study Comparative Study Observational Study
Comparison of incidence of anaphylaxis between sugammadex and neostigmine: a retrospective multicentre observational study.
In Japan, Sugammadex anaphylaxis occurs in ~1 in 5,000 exposures.
pearl -
Syringe infusion pumps are used for the precise continuous administration of intravenous drugs. Their compliance and mechanical deficiencies have been found to cause considerable start-up delays, flow irregularities during vertical displacement, as well extensive delays of occlusion alarms at low infusion rates. The aim of this study was to evaluate the performance of several modern syringe infusion pumps at low infusion rates and the impact on drug concentration. ⋯ Problems with the performance of syringe infusion pump assemblies can have considerable impact on plasma drug concentration when highly concentrated short-acting cardiovascular drugs are administered at low flow rates. The problems, which affected all assemblies tested, are mainly related to the functional principle of syringe infusion pumps and will only partially be solved by incremental improvements of existing equipment.
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Editorial Comment
Can we go too far with empathy? Shifting from empathy to compassion.