International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2015
The use of paracetamol (acetaminophen) among a community sample of people with chronic non-cancer pain prescribed opioids.
The regular use of simple analgesics in addition to opioids such as paracetamol (or acetaminophen) is recommended for persistent pain to enhance analgesia. Few studies have examined the frequency and doses of paracetamol among people with chronic non-cancer pain including use above the recommended maximum daily dose. ⋯ The majority of people with chronic non-cancer pain prescribed opioids report using paracetamol appropriately. High income, use of paracetamol/opioid combination analgesics and higher opioid dose were independently associated with paracetamol use above the recommended maximum daily dose.
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Int. J. Clin. Pract. · Nov 2015
Zopiclone use associated with increased risk of acute pancreatitis: a case-control study in Taiwan.
The purpose of this study was to assess the relationship between zopiclone use and the risk of acute pancreatitis in Taiwan. ⋯ Subjects actively using zopiclone are associated with increased risk of acute pancreatitis. Clinicians should take acute pancreatitis risk into account when prescribing zopiclone, particularly comorbid with alcohol-related disease or biliary stone.