International journal of clinical practice
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Int. J. Clin. Pract. · Oct 2021
ReviewPrognostic impact of comorbidity measures on outcomes following acute coronary syndrome: a systematic review.
To identify existing comorbidity measures and summarise their association with acute coronary syndrome (ACS) outcomes. ⋯ The review summarised different comorbidity measures and reported that higher comorbidity scores were associated with worse ACS outcomes. The CCI is the most widely measure of comorbid burden and shows additive value to clinical risk scores in use.
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Int. J. Clin. Pract. · Oct 2021
ReviewOptical Coherence Tomography in Peripheral Arterial Disease: A Systematic Review.
Optical coherence tomography (OCT) is a novel adjunct in the field of medicine. The objective of this systematic review was to evaluate the role of OCT in the field of contemporary endovascular surgery in terms of its utility in diagnostics and interventions in peripheral arterial disease (PAD). ⋯ Although there is currently no level 1 evidence to suggest routine use of OCT in the diagnosis and treatment of PAD, current literature suggests that the use of OCT is safe and effective. The OCT real-time vessel wall structural images clearly distinguish normal anatomy from plaque pathology, and are of great advantage both in the accurate diagnosis and treatment of target lesion, especially in reducing the amount of radiation in the endovascular procedure.
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Int. J. Clin. Pract. · Oct 2021
Meta AnalysisThe association of dietary energy density and the risk of obesity, type 2 diabetes and metabolic syndrome: a systematic review and meta-analysis of observational studies.
There is a growing body of evidence linking dietary energy density (DED) with metabolic disorders like obesity, type 2 diabetes (T2D) and metabolic syndrome (MetS). However, according to our knowledge, there has been no systematic review and mate-analysis on T2D and MetS with DED. Therefore, this study aimed to investigate the association between DED with the risk of obesity, T2D and MetS in a systematic review and meta-analysis of observational studies. ⋯ In this systematic review and meta-analysis of observational studies, we found that the DED increased the risk of T2D and MetS but was not significant with the risk of obesity.
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Int. J. Clin. Pract. · Oct 2021
Meta AnalysisEffect of age of COVID-19 inpatient on the severity of the disease: A meta-analysis.
Clinical symptoms of adults and paediatric inpatients with COVID-19 disease are conflicting. This meta-analysis was conducted to assess the effect of age of COVID-19 inpatient on the severity of the disease. ⋯ Adults with COVID-19 disease have a much higher level of symptomatic severity, fever and CT-positive COVID-19 disease than children. However, as shown in our results, the laboratory data were similar in both groups.
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Int. J. Clin. Pract. · Oct 2021
Multicenter StudyLow-value injury admissions in an integrated Canadian trauma system: a multicenter cohort study.
Injury represents 260 000 hospitalisations and $27 billion in healthcare costs each year in Canada. Evidence suggests that there is significant variation in the prevalence of hospital admissions among emergency department presentations between countries and providers, but we lack data specific to injury admissions. We aimed to estimate the prevalence of potentially low-value injury admissions following injury in a Canadian provincial trauma system, identify diagnostic groups contributing most to low-value admissions and assess inter-hospital variation. ⋯ One out of six hospital admissions following injury may be of low value. Children with mild traumatic brain injury and adults with superficial injuries could be good targets for future research efforts seeking to reduce healthcare services overuse. Inter-hospital variation indicates there may be an opportunity to reduce low-value injury admissions with appropriate interventions targeting modifications in care processes.