International journal of clinical practice
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Int. J. Clin. Pract. · Oct 2021
The role of lactate dehydrogenase-to-albumin ratio in clinical evaluation of adult-onset Still's disease.
The aim of the study is to evaluate the importance of lactate dehydrogenase-to-albumin ratio (LAR) in patients with adult-onset Still's disease (AOSD) and to investigate the relationship between this ratio and clinical laboratory variables. ⋯ LAR can be a valuable inflammatory marker to determine AOSD patients with organ involvement and higher ferritin level.
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Int. J. Clin. Pract. · Oct 2021
Pediatric Lichen Sclerosus et Atrophicus: A Retrospective Analysis of 38 Pediatric Patients.
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory cutaneous disease. ⋯ LSA can be asymptomatic in the majority of affected children. Diagnostic delay was noted in 80% of the study's LSA patients, highlighting the lack of awareness of the condition among parents and clinicians.
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Int. J. Clin. Pract. · Oct 2021
Comparison of Rapid Antibody Test and Thorax Computed Tomography Results in Patients who Underwent RT-PCR with the Pre-Diagnosis of COVID-19.
In this study, it is planned to compare the real-time reverse transcription-polymerase chain reaction (RT-PCR) test, which is the gold standard in the diagnosis of COVID-19, with thorax computed tomography (CT) and rapid antibody test results. ⋯ Rapid antibody test and thorax CT examinations were found to have low diagnostic value in patients who admitted to the emergency department of our hospital and whose first RT-PCR SARS-CoV-2 test was positive. Studies involving larger patient groups are needed for their use alone in diagnosis and screening.
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Int. J. Clin. Pract. · Oct 2021
Serum neuregulin 4 (NRG-4) level and non-alcoholic fatty liver disease (NAFLD): a case-control study.
The current case-control study aimed to examine the association of circulating neuregulin 4 (NRG-4), a brown fat-enriched endocrine factor, with non-alcoholic fatty liver disease (NAFLD). ⋯ The results of the present study demonstrate that circulating NRG-4 levels may play a protective role in NAFLD.
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Galectin-3 is a β-galactoside-binding lectin associated with cellular proliferation, inflammation and angiogenesis, which are the major characteristics of psoriatic skin. ⋯ Elevated serum galectin-3 levels in psoriasis patients may indicate a possible role of galectin-3 in pathogenesis of psoriasis.