International journal of clinical practice
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Int. J. Clin. Pract. · Oct 2021
Meta AnalysisEfficacy and safety of phytoestrogens in the treatment of perimenopausal and postmenopausal depressive disorders: a systematic review and meta-analysis.
Depression is one of the most common and specific symptoms among menopausal women, leading to significant personal, family, and economic burdens. Some studies have shown that phytoestrogens can help relieve symptoms of depression. ⋯ Phytoestrogen can relieve depression symptoms among menopausal, especially for postmenopausal women who take low doses(25 mg/d ≤ dose ≤ 100 mg/d) of phytoestrogens for a long-term duration. Although mild adverse reactions have been reported, phytoestrogen could be considered as a complementary treatment for postmenopausal depression.
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Int. J. Clin. Pract. · Oct 2021
ReviewCurcumin and rheumatoid arthritis: A systematic review of literature.
Curcumin is a natural polyphenol and the main compound from the rhizome of Turmeric (Curcuma longa) and other Curcuma species. It has been widely used for different medical purposes, such as improvement of pain and inflammatory conditions in various diseases. ⋯ In conclusion, curcumin seems to be useful, and it is recommended that more human studies be performed to approve the cellular and animal results and determine the effective and optimal doses of curcumin on RA patients.
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Int. J. Clin. Pract. · Oct 2021
Randomized Controlled TrialDoes heated erythrocyte suspension transfusion with medical devices containing phthalates increase DEHP and MEHP levels?
It is commonly known that stored blood and blood products are heated before transfusion to prevent hypothermia, which leads to increased di-(2-ethylhexyl) phthalate (DEHP) content leaching into the blood and blood products and thereby causes greater conversion of DEHP to mono (2-ethylhexyl) phthalate (MEHP). However, there has been no study in the literature reporting on the amount of toxic phthalates in blood following the erythrocyte suspension (ES) transfused via warming. In this study, we aimed to investigate the DEHP and MEHP content in blood following the heated ES transfusions administered by DEHP-containing and DEHP-free infusion sets. ⋯ DEHP-containing products lead to toxicity. Therefore, using DEHP-free medical devices may prevent toxicity in patients undergoing ES transfusion.
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Int. J. Clin. Pract. · Oct 2021
Randomized Controlled TrialMelissa officinalis tea favorably affects the frequency of premature ventricular beats and cardiometabolic profile among patients with premature ventricular contraction (PVC): A randomized open-label controlled trial.
Premature ventricular contraction (PVC) as one of the most common arrhythmias could worsen the morbidity of cardiovascular events, particularly concurrent with other risk factors. Considering the probable side effects of antiarrhythmic drugs chronic use, prescribing herbal medicines for such conditions is on the rise. Melissa officinalis (MO) is widely identified as an antiarrhythmic and cardioprotective agent but there is limited evidence for its clinical use. This research, thus, aimed to investigate the effects of MO tea among patients with PVCs. ⋯ Together, these results seem to support the higher cardioprotective effects of MO as a medicinal plant than lifestyle modifications alone. Nevertheless, further exploration of this hypothesis is warranted using large-scaled clinical trials.
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Int. J. Clin. Pract. · Oct 2021
The interaction of aging with serum 25(OH)D and 1,25(OH)2 D status on muscle strength.
To investigate the combination relationship of age with serum 25-hydroxyvitamin D (25(OH) D) and 1,25-(OH)2D3 levels on muscle strength. ⋯ Serum 25(OH)D and 1,25(OH)2 D were not related to muscle strength. However, age, and combination of age with both 25(OH)D and 1,25(OH)2 D, significantly resulted in improving in muscle strength up to middle age.