International journal of clinical practice
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Int. J. Clin. Pract. · Mar 2021
Thoracic endosonography (EBUS/EUS-b) in diagnosis of different intrathoracic diseases: a 4-year experience at a single-center in Greece.
In the last decade, the advent of thoracic endosonography has revolutionised the field of diagnostic bronchoscopy. ⋯ Thoracic endosonography is an efficient, safe, minimally invasive tool yielding high sensitivity and diagnostic accuracy in patients with suspected malignancy and mediastinal lymphadenopathy. Experienced pulmonologists in EBUS-TBNA should more routinely perform EUS-b FNA to avoid unnecessary surgical interventions.
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Int. J. Clin. Pract. · Mar 2021
Identifying the predictors of estimated glomerular filtration rate after partial nephrectomy with a nonlinear regression model.
To evaluate the effect of partial nephrectomy on renal function and to identify predictors of estimated glomerular filtration rate (eGFR) at 6 months after partial nephrectomy. ⋯ Baseline eGFR values, tumour size, and presence of hypertension are significant predictors of eGFR values in the mid-term in patients undergoing partial nephrectomy.
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Int. J. Clin. Pract. · Mar 2021
The Modulating Effect of Dietary Protein Intake on Mortality in Long-term Hemodialysis Patients: A Nationwide Population-based Study.
A high prevalence of protein-energy wasting and malnutrition among uremic patients is associated with an increase in morbidity and mortality. We aimed to investigate the modulating effect of daily dietary protein intake (DPI) evaluated by normalised protein catabolic rate (nPCR) on mortality in long-term haemodialysis (HD) patient from a nationwide population-based study. ⋯ Low DPI (as presented by nPCR) independently correlated with all-cause and CV mortality among HD patients. Mortality risks were higher in low DPI patients even with normoalbuminaemia and non-hypocholesterolaemia. Further investigations on the importance of increasing DPI in HD patients is warranted.
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Int. J. Clin. Pract. · Mar 2021
Adherence to methotrexate therapy in Polish patients with inflammatory joint diseases.
Methotrexate (MTX) is the first-line medicine used in most inflammatory joint diseases. It is highly effective but, it's burdened with common side effects and the result of treatment is not immediately visible. This fact significantly increases the risk of unsatisfying patients' compliance. It may lead to difficulties in achieving disease remission and unjustified escalation of treatment. ⋯ High adherence with prescribed MTX is associated with good treatment tolerance, while the occurrence of side effects significantly increases the risk of discontinuation, often without consulting the physician.
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Int. J. Clin. Pract. · Mar 2021
Ferritin index is a strong prognostic marker in Adult Hemophagocytic Lymphohistiocytosis.
The relationship between ferritin levels and survival in adult hemophagocytic lymphohistiocytosis (HLH) has been evaluated in previous studies. However, Admission-to-discharge percentage ferritin reduction (named as ferritin index) level in adult patients with HLH has never been evaluated to predict 6-month survival. ⋯ Ferritin index is a better predictor of 6-month survival than admission and discharges ferritin levels in adult patients with HLH.