International journal of clinical practice
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Int. J. Clin. Pract. · Aug 2021
Randomized Controlled TrialA Double-Blind, Controlled, Crossover Trial of Amlodipine on Iron Overload Status in Transfusion Dependent ꞵ-Thalassemia Patients.
This study examined whether administration of amlodipine could improve myocardial iron loading status in patients with transfusion dependent β-thalassemia (TDT), through a placebo-controlled, crossover study. ⋯ Amlodipine might improve myocardial MRI T2* and serum ferritin level compared to placebo. However, larger clinical studies are needed to confirm the results.
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Int. J. Clin. Pract. · Aug 2021
Randomized Controlled TrialEfficacy of various laser devices on lithotripsy in retrograde intrarenal surgery used to treat 1-2 cm kidney stones: A prospective randomized study.
To compare the efficacy of different laser devices and power ranges on lithotripsy in retrograde intrarenal surgery (RIRS) for 1-2 cm kidney stones. ⋯ The 30 W laser device used in RIRS for 1-2 cm kidney stones had shorter operation times, higher SFRs, and lower post-operative pain scores compared with the 20 W device. The 30 W laser device is safe and more efficient in RIRS for treatment of 1-2 cm kidney stones.
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Int. J. Clin. Pract. · Aug 2021
Multicenter StudyPredicting all-cause unplanned readmission within 30 days of discharge using electronic medical record data: a multi-center study.
To develop a predictive model for identifying patients at high risk of all-cause unplanned readmission within 30 days after discharge, using administrative data available before discharge. ⋯ We propose a 10-item predictive model to flag high-risk patients in a diverse population before discharge using readily available hospital administrative data which can easily be integrated into the hospital information system.
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Int. J. Clin. Pract. · Aug 2021
Multicenter StudyThe Effect of Risk Factors on Surgical and Oncological Results in High - Risk Prostate Cancer: A Multicenter Study of the Urooncology Society, Turkey.
To evaluate the effect of risk factors and selected surgical methods on operative and oncological results of patients undergoing radical prostatectomy (RP) with high-risk prostate cancer (HRPC). ⋯ RP alone is an effective treatment in the majority of patients with HRPC and PLND did not affect the progression rates after RP. According to the number of pre-operative high-risk features, as the number of risk factors increases, there is a need for additional treatment.
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Int. J. Clin. Pract. · Aug 2021
Mapping the role of pH-adjusted potassium in diabetic ketoacidosis: Hypokalemia and the patient outcomes.
Incidence of hypokalemia during the management of diabetic ketoacidosis (DKA) is high despite detailed potassium replacement guidelines in its treatment. ⋯ pH-adjusted potassium shall be used as a marker for hypokalemia and to initiate potassium replacement instead of measured serum potassium in DKA. Utilising pHK will help to avoid hypokalemia, reduce its severity and shorten ED care which will subsequently reduce hospitalisation length. We expect pHK to improve pharmacoeconomics in the future.