International journal of clinical practice
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Int. J. Clin. Pract. · Aug 2021
Knowledge and awareness of the general population and healthcare providers about retinoblastoma: it is time to know the glow.
Retinoblastoma is the most frequent primary intraocular tumour in childhood. Early detection of retinoblastoma is the key to successful management with a higher chance of survival. This study aims to assess the knowledge of the general population and healthcare providers about retinoblastoma in term of presentation, risk factors, timing for diagnosis, and complications. ⋯ However, the awareness and knowledge about retinoblastoma are very limited in our study population. Efforts should be directed at increasing awareness of both the general population and healthcare providers regarding retinoblastoma. Policymakers are responsible for improving knowledge and awareness about retinoblastoma to facilitate early detection of the disease by conducting awareness campaigns in addition to improve screening skills of healthcare providers and providing them with proper screening and diagnostic tools.
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Int. J. Clin. Pract. · Aug 2021
Are the kidneys involved in lipoid proteinosis? Study of 22 patients.
Lipoid proteinosis (LP) is a systemic, progressive, rare genodermatosis that manifests in early life with mucocutaneous lesions. Kidney involvement has not been described before, hence we aimed to investigate kidney findings in LP patients. ⋯ Multiple simple renal cysts were detected in the majority of LP patients, and this finding could be part of the systemic involvement of the disease. Renal functions and biochemical parameters were within the normal reference range, but low serum albumin and high C-reactive protein levels in LP patients may be the signs of elevated systemic inflammation. Although more studies are needed to better define these findings, the presence of many simple renal cysts in LP patients was found to be the most important finding of this study.
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Int. J. Clin. Pract. · Aug 2021
The agreement between arterial and venous lactate in patients with sepsis.
Arterial sampling, which is the gold standard for measuring lactate levels in sepsis, is more painful, requires experience and is associated with a higher incidence of morbidity, when compared with venous sampling. This study attempted to measure the correlation and agreement between arterial and peripheral venous (PV) lactate and between arterial and central venous (CV) lactate, with the objective to test interchangeability of the two and possibly support the use of venous lactate levels in resuscitating patients with sepsis. ⋯ Our study demonstrates a high level of agreement in the lactate levels as measured on venous samples and arterial samples. Venous lactate levels are reliable in resuscitation of patients with sepsis.
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Int. J. Clin. Pract. · Aug 2021
Rectal Spacers in Patients with Prostate Cancer Undergoing Radiotherapy: A Survey of UK Uro-Oncologists.
To understand the awareness and use of rectal spacers for prostate cancer patients undergoing radical radiotherapy in the United Kingdom. ⋯ The current use of rectal spacers by UK uro-oncologists for patients with localised or locally advanced prostate cancer receiving radiotherapy is low and largely restricted by resourcing issues.
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Int. J. Clin. Pract. · Aug 2021
Observational StudyAdmission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short and long-term mortality risk.
Our study was carried out on patients admitted to the emergency ward with acute stroke symptoms that were subsequently diagnosed with cerebrovascular disease. We aimed to examine the relationship between these patients' admission lactate levels and their 1-, 3-, and 12-month mortality rates in order to evaluate the prognostic value of lactate levels. ⋯ Our study found that hyperlactatemia was associated with a higher risk of 1-, 3-, and 12-month mortality, suggesting that it has predictive prognostic value. In the future, we believe that prospective observational studies and/or large-scale retrospective studies will be of great value in providing more insight into this topic.