International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2015
Admission serum magnesium levels and the risk of acute respiratory failure.
The association between admission serum magnesium (Mg) levels and risk of acute respiratory failure (ARF) in hospitalised patients is limited. The aim of this study was to assess the risk of developing ARF in all hospitalised patients with various admission Mg levels. ⋯ Both admission hypomagnesemia and hypermagnesemia were associated with an increased risk for in-hospital ARF.
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Int. J. Clin. Pract. · Nov 2015
Randomized Controlled Trial Multicenter StudyInterventions do not enhance medication persistence and compliance in patients with overactive bladder: a 24 weeks, randomised, open-label, multi-center trial.
Anticholinergics are currently the mainstay for the management of overactive bladder (OAB). However, low drug adherence has been noted with these medications. The aim of this study was to determine whether a health education intervention (HEI) could improve drug persistence with anticholinergics in OAB patients. ⋯ The health education intervention was not effective to increase drug persistence in OAB patients on anticholinergics.
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Int. J. Clin. Pract. · Oct 2015
Review Meta AnalysisShould patients prescribed long-term low-dose aspirin receive proton pump inhibitors? A systematic review and meta-analysis.
Several clinical guidelines recommend the use of proton pump inhibitors (PPIs) in patients taking low-dose aspirin but report no or limited supporting data. We conducted a systematic review and meta-analysis to examine the effects of co-administration of PPIs in patients taking low-dose aspirin on the risks of adverse gastrointestinal (GI) and cardiovascular (CV) events, and on patient adherence to aspirin. ⋯ The practice of co-prescribing PPIs in patients taking low-dose aspirin is supported by some data, but the evidence is rather weak. It currently remains unclear whether the benefits of co-administration of PPIs in users of low-dose aspirin outweigh their potential harms.
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Int. J. Clin. Pract. · Oct 2015
ReviewBarriers and facilitators to starting insulin in patients with type 2 diabetes: a systematic review.
To identify the barriers and facilitators to start insulin in patients with type 2 diabetes. ⋯ Major barriers to insulin initiation persist despite availability of newer and safer insulin. Healthcare professionals should explore and address these barriers. Targeted interventions should be developed to overcome these barriers.