European journal of pain : EJP
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β-Blockers reduce temporomandibular joint (TMJ) pain. We asked whether they also reduce TMJ inflammation and, if so, whether this anti-inflammatory effect contributes to its analgesic action. ⋯ β-Blockers have an anti-inflammatory effect on temporomandibular joint (TMJ) that contributes to its analgesic effect. The results of this work suggest that β-blockers can be used to treat the painful conditions of TMJ, especially when they are associated with an inflammatory process.