The British journal of surgery
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Review Meta Analysis
Meta-analysis of contemporary short- and long-term mortality rates in patients diagnosed with critical leg ischaemia.
Critical leg ischaemia (CLI) has been associated with high mortality rates. There is a lack of contemporary data on both short- and long-term mortality rates in patients diagnosed with CLI. ⋯ Early mortality rates in patients diagnosed with CLI have improved slightly compared with previous historical data, but long-term mortality rates are still high.
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Comparative Study
Clinical trial of combined radio- and fluorescence-guided sentinel lymph node biopsy in breast cancer.
Combining radioactive colloids and a near-infrared (NIR) fluorophore permits preoperative planning and intraoperative localization of deeply located sentinel lymph nodes (SLNs) with direct optical guidance by a single lymphatic tracer. The aim of this clinical trial was to evaluate and optimize a hybrid NIR fluorescence and radioactive tracer for SLN detection in patients with breast cancer. ⋯ NTR3685 (Netherlands Trial Register; http://www.trialregister.nl).