The British journal of surgery
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Review Meta Analysis
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss.
Tranexamic acid (TXA) reduces blood transfusion in surgery but the extent of the reduction in blood loss and how it relates to the dose of TXA is unclear. ⋯ TXA reduces blood loss in surgical patients by about one-third. A total dose of 1 g appears to be sufficient for most adults. There is no evidence to support the use of high doses.
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Multicenter Study Comparative Study
Predicting aortic complications after endovascular aneurysm repair.
Lifelong surveillance is standard after endovascular repair of abdominal aortic aneurysm (EVAR), but remains costly, heterogeneous and poorly calibrated. This study aimed to develop and validate a scoring system for aortic complications after EVAR, informing rationalized surveillance. ⋯ The risk score uses commonly available morphological data to stratify the rate of complications after EVAR. The proposals for rationalized surveillance could provide clinical and economic benefits.
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Multicenter Study Comparative Study
Outcome following laparoscopic and open total mesorectal excision for rectal cancer.
There are few reports on the oncological quality of resection and outcome after laparoscopic versus open total mesorectal excision (TME) for rectal cancer in everyday surgical practice. ⋯ Oncological outcome is comparable after laparoscopic and open TME in everyday surgical practice.
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Randomized Controlled Trial Comparative Study
Randomized clinical trial of the benefit of laparoscopy with closure of loop ileostomy.
The aim was to compare reversal and laparoscopy with standard reversal of loop ileostomy in terms of hospital stay and morbidity in a randomized study. ⋯ ISRCTN46101203 (http://www.controlled-trials.com).
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Randomized Controlled Trial
Randomized clinical trial of a simple pulmonary recruitment manoeuvre to reduce pain after laparoscopy.
Shoulder tip and abdominal pain following laparoscopic procedures are well recognized causes of postoperative morbidity. In this double-blind randomized clinical trial attempts were made to reduce postoperative pain in patients undergoing laparoscopic surgery by implementing a simple intraoperative technique. ⋯ NCT01720433 (http://www.clinical trials.gov).