The British journal of surgery
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Observational Study
Magnetic resonance tumour regression grade and pathological correlates in patients with rectal cancer.
Evidence to support the specific use of magnetic resonance tumour regression grade (mrTRG) is inadequate. The aim of this study was to investigate the pathological characteristics of mrTRG after chemoradiotherapy (CRT) for rectal cancer and the implications for surgery. ⋯ Patients with mrTRG1 without tumour spread may be suitable for TAE.
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Lymph node regression and survival following neoadjuvant chemotherapy in oesophageal adenocarcinoma.
The aim was to define the pathological response in lymph nodes following neoadjuvant chemotherapy for oesophageal adenocarcinoma and to quantify any associated survival benefit. ⋯ Lymph node regression is a strong prognostic factor and may be more important than response in the primary tumour.
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Definitions of regional lymph nodes for gallbladder cancer differ according to staging system. Hence, the appropriate extent of lymph node dissection has not yet been standardized. ⋯ PSPLNs and nodes along the hepatoduodenal ligament and hepatic artery should be considered regional nodes for gallbladder cancer, and should be resected.