The British journal of surgery
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Multicenter Study Comparative Study Observational Study
Hepatectomy versus systemic therapy for liver-limited BRAF V600E-mutated colorectal liver metastases: multicentre retrospective study.
To date, only two studies have compared the outcomes of patients with liver-limited BRAF V600E-mutated colorectal liver metastases (CRLMs) managed with resection versus systemic therapy alone, and these have reported contradictory findings. ⋯ BRAF V600E mutation should not be considered a contraindication to surgery for patients with resectable, liver-only CRLMs.