The British journal of surgery
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Skin blood flow (SBF) values were estimated on the posterior, medial and lateral aspects of the lower leg in 47 patients presenting for assessment of amputation level. Measurement was made using a radioisotope (iodoantipyrine) clearance technique. ⋯ The results gave significantly higher SBFs on the medial and posterior aspects of the ischaemic leg. The finding of an uneven distribution of blood flow at the below knee amputation level has important implications in the planning of amputation flaps.
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Comparative Study Clinical Trial
Towards the Belfast immunosuppressive regimen: a prospective trial of low versus high dose steroids and once versus twice daily immunosuppression.
The Transplant Unit in Belfast achieves the highest survival rates in Great Britain for renal transplants. The immunosuppression used comprises azathioprine and very low doses of steroids administered just once a day. ⋯ None the less, with low doses of steroids the complications of cushingism and obesity were markedly reduced. Neither trial achieved the degree of success in transplant survival that has been usual in Belfast.