The British journal of surgery
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This was a single-centre, retrospective study of transgender women undergoing genital gender-affirming surgery. A chart study was conducted, recording individual demographics, all genital surgical procedures, and surgical techniques. Procedure incidence, techniques employed, and demographic variations over the years were analysed.
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Meta Analysis Comparative Study
Neoadjuvant therapy versus direct to surgery for T4 colon cancer: meta-analysis.
Despite persistently poor oncological outcomes, approaches to the management of T4 colonic cancer remain variable, with the role of neoadjuvant therapy unclear. The aim of this review was to compare oncological outcomes between direct-to-surgery and neoadjuvant therapy approaches to T4 colon cancer. ⋯ Compared with direct to surgery, neoadjuvant therapy improves margin-negative resection rates and overall survival.