The British journal of surgery
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Multicenter Study Clinical Trial
Prophylactic nipple-sparing mastectomy with immediate breast reconstruction: results of a French prospective trial.
Nipple-sparing mastectomy (NSM) with immediate breast reconstruction (IBR) is used increasingly when performing a prophylactic mastectomy. Few prospective studies have reported on complication rates. This complementary trial to the French prospective multicentre MAPAM trial aimed to evaluate the nipple-areola complex (NAC) necrosis rate in prophylactic NSM with IBR. ⋯ Results of this prospective study confirm that prophylactic NSM with IBR is associated with a low risk of total NAC necrosis.
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Long-term results after non-operative treatment for children with simple appendicitis seem promising, possibly avoiding appendicectomy in 70 per cent of children after a median follow-up of 5 years. The need for delayed appendicectomy more than 2 years after the initial treatment is rare (0–5 per cent) and no complications occurred past 1 year, including children who underwent delayed appendicectomy.