Critical care : the official journal of the Critical Care Forum
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Randomized Controlled Trial Multicenter Study
Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands.
Procalcitonin (PCT) testing can help in safely reducing antibiotic treatment duration in intensive care patients with sepsis. However, the cost-effectiveness of such PCT guidance is not yet known. ⋯ Although the impact of PCT guidance on total healthcare-related costs during the initial hospitalisation episode is likely negligible, the lower in-hospital mortality may lead to a non-significant increase in costs over a one-year time horizon. However, since uncertainty remains, it is recommended to investigate the long-term cost-effectiveness of PCT guidance, from a societal perspective, in different countries and settings.
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Comment Letter
A brief comment on the predictive value of myeloperoxidase-conjugated DNA level in patients with septic shock.
Abstract
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Randomized Controlled Trial
Bright environmental light improves the sleepiness of nightshift ICU nurses.
Shift work can disturb circadian homeostasis and result in fatigue, excessive sleepiness, and reduced quality of life. Light therapy has been shown to impart positive effects in night shift workers. We sought to determine whether or not prolonged exposure to bright light during a night shift reduces sleepiness and enhances psychomotor performance among ICU nurses. ⋯ A bright lighting environment for ICU nurses working the night shift reduces sleepiness but increases the number of psychomotor errors.
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Abstract
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Abstract