Neuromodulation : journal of the International Neuromodulation Society
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Some patients with spasticity and pain in the extremities fail to respond to increases in the dose of intrathecally delivered baclofen. ⋯ We suggest that in patients who experience symptom aggravation at increased ITB doses, potential causative factors and ITB system malfunction should first be ruled out, and consideration should then be given to decreasing the ITB dose.