Neuromodulation : journal of the International Neuromodulation Society
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Transcranial direct current stimulation (tDCS) is an emerging neuromodulation technique. The effect of tDCS can vary significantly depending on electrode position and current intensity, making it crucial to find an optimized tDCS montage. However, because of the high computational load, most tDCS optimization approaches have been performed with a limited number of candidates for electrode positions, such as 10-10 or 10-20 international channel configurations. This study introduced the Bayesian optimization and hyperband (BOHB) method to seek optimal tDCS montage for the entire human scalp without conventional constraints. ⋯ The BOHB method performed better than did the random search approach. Thus, the BOHB method is feasible for tDCS optimization and can be used as an optimal stimulation montage seeker by fine-tuning some control parameters.
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Transcranial temporal interference stimulation (tTIS) is a novel, noninvasive neuromodulation technique to modulate deep brain neural activity. Despite its potential, direct electrophysiological evidence of tTIS effects remains limited. This study investigates the impact of tTIS on local field potentials (LFPs) in the deep brain using minipigs implanted with deep brain electrodes. ⋯ These findings indicate that tTIS can regulate LFP changes in the deep brain, highlighting its potential as a promising tool for future noninvasive neuromodulation applications.
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YouTube is an important source of medical information for various medical topics and procedures. The purpose of the present study is to appraise the quality of medical information available on YouTube on the topic of peripheral nerve stimulation (PNS) for chronic pain. ⋯ YouTube videos on PNS stimulation for chronic pain are low to moderate in quality. Videos from academic sources were higher in quality than were private practice videos. Furthermore, videos with above-average view counts had lower mean scores on all three instruments, suggesting most of the viewership had watched lower-quality video content.
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Standard anterograde placement of a surgical paddle lead (SPL) for spinal cord stimulation (SCS) can be challenging in patients with scarring from prior spine surgery, instrumentation obstructing the targeted level, or severe stenosis below the targeted level. One potential alternative is retrograde (caudal) insertion by performing laminotomies cephalad to the targeted levels. The literature is limited to only a small number of individual cases describing this technique. In this report, the authors present their experience over the last ten years of the retrograde insertion of SPLs for SCS. ⋯ The retrograde insertion of SPLs is a low-risk and feasible procedure that can be performed with minimal risk of lead migration, fracture, or deep surgical site infection. The retrograde strategy can be used in SPL trials or permanent placements.
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Ultrahigh frequencies (UHF) have been shown to selectively suppress the sensory pathway with a rapid onset and prolonged effect compared with low frequencies. Few studies have explored the feasibility of UHF electrical stimulation in treating overactive bladder. This study aimed to investigate whether bladder overactivity could be inhibited by UHF stimulation at the L6 nerve root. ⋯ This preliminary study provides evidence for UHF stimulation of the L6 spinal nerve root, analogous to the sacral nerve root in humans, as a potential alternative neuromodulation technique to suppress bladder overactivity.