Current opinion in clinical nutrition and metabolic care
-
Curr Opin Clin Nutr Metab Care · Nov 2008
ReviewThe impact of music on hypermetabolism in critical illness.
Although the literature on complementary therapy, including music, is vast, there are few studies conducted in a scientific fashion exploring physiologic mechanisms. This review summarizes recent evidence on the effects of music on the hypermetabolic response of critical illness. ⋯ Music may play an important role as an adjunct therapy in critical care. However, further studies are necessary to elucidate how music can be further integrated clinically and the precise underlying mechanisms of its beneficial effects.
-
Almost 15 years after its initial proposal, the astrocyte-neuron lactate shuttle hypothesis still occupies the center stage in research on brain energetics. Recent developments have provided further evidence for its validity and have extended its application to different areas of neuroscience. ⋯ Brain energetics has undertaken its revolution. A new concept based on metabolic compartmentalization between astrocytes and neurons is establishing itself as the leading paradigm that opens new perspectives in areas such as functional brain imaging and regulation of energy homeostasis.
-
Curr Opin Clin Nutr Metab Care · Sep 2008
ReviewNoninvasive glycaemia monitoring: background, traditional findings, and novelties in the recent clinical trials.
The noninvasive measurement of glycaemia is a topic of great interest and is rapidly changing; novelties have emerged frequently in the last years. The aim of the present review is to briefly present the main technologies in the field and the devices recently developed based on them. ⋯ The development of reliable methods for noninvasive glycaemia monitoring would have a tremendous impact on diabetes management. The most recent device prototypes appear promising, but because of the failure of previous projects, the assessment of such new devices must be done with extreme caution.
-
Curr Opin Clin Nutr Metab Care · Sep 2008
ReviewSpecial commentary: a call for intensive metabolic support.
This special commentary addresses recent clinical reviews regarding appropriate nutrition and metabolic support in the critical care setting. ⋯ It is proposed that intensive metabolic support be routinely implemented in the intensive care unit based on the following steps: intensive insulin therapy with an appropriate blood glucose target, nutrition risk assessment, early and if needed combined enteral nutrition and parenteral nutrition to target 20-25 kcal/kg/day and 1.2-1.5 g protein/kg/day, and nutritional and metabolic monitoring.