Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Jul 2006
A method to estimate the depth of the sciatic nerve during subgluteal block by using thigh diameter as a guide.
The subgluteal approach is common for sciatic nerve block. Although the surface landmarks are clear, the depth of this nerve at this level is difficult to judge. The purpose of this study is to establish a method of estimating the sciatic nerve depth using the anteroposterior (AP) diameter of the thigh as a marker. ⋯ Comparing phase 1 and phase 2 datasets shows the slopes of linear regression lines are nearly parallel. The clinical data from phase 2 verify the anatomical data collected in phase 1 and show that the sciatic nerve depth to AP diameter ratio is 0.43 or the depth of the sciatic nerve is approximately 43% of thigh diameter if the patient is positioned in the lateral decubitus position.
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Reg Anesth Pain Med · Jul 2006
Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart.
Infusion of a lipid emulsion has been advocated for treatment of severe bupivacaine cardiac toxicity. The mechanism of lipid rescue is unknown. These studies address the possibility that lipid infusion reduces cardiac bupivacaine content in the context of cardiac toxicity. ⋯ Lipid emulsion speeds loss of bupivacaine from cardiac tissue while accelerating recovery from bupivacaine-induced asystole. These findings are consistent with the hypothesis that bupivacaine partitions into the emulsion and supports the concept of a "lipid sink." However, the data do not exclude other possible mechanisms of action.